7MX2

Cryo-EM structure of human ternary NatC complex with a Bisubstrate inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004596	molecular_function	protein-N-terminal amino-acid acetyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0017196	biological_process	N-terminal peptidyl-methionine acetylation
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005844	cellular_component	obsolete polysome
B	0017196	biological_process	N-terminal peptidyl-methionine acetylation
B	0031417	cellular_component	NatC complex
B	0043066	biological_process	negative regulation of apoptotic process
B	0048659	biological_process	smooth muscle cell proliferation
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005844	cellular_component	obsolete polysome
C	0031417	cellular_component	NatC complex
C	0043066	biological_process	negative regulation of apoptotic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	148
Details	Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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