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7MX2

Cryo-EM structure of human ternary NatC complex with a Bisubstrate inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
N-alpha-acetyltransferase 35, NatC auxiliary subunitpolymer72583754.01UniProt (Q5VZE5)
Pfam (PF04112)
Homo sapiens (human)Embryonic growth-associated protein homolog,Protein MAK10 homolog
2B
(C)
N-alpha-acetyltransferase 38, NatC auxiliary subunitpolymer12513530.31UniProt (Q9BRA0)
Pfam (PF01423)
Homo sapiens (human)LSM domain-containing protein 1,Phosphonoformate immuno-associated protein 2
3C
(A)
N-alpha-acetyltransferase 30polymer15218083.31UniProt (Q147X3)
Pfam (PF00583)
Homo sapiens (human)N-acetyltransferase 12,N-acetyltransferase MAK3 homolog,NatC catalytic subunit
4D
(D)
peptide portion of bisubstrate inhibitorpolymer4416.51Homo sapiens
5E
(D)
CARBOXYMETHYL COENZYME *Anon-polymer825.61Chemie (CMC)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight115784.1
Non-Polymers*Number of molecules1
Total formula weight825.6
All*Total formula weight116609.7
*Water molecules are not included.

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PDB entries from 2025-10-15

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