7MSG

The crystal structure of LIGHT in complex with HVEM and CD160

7MSG の概要

• エントリーDOI: 10.2210/pdb7msg/pdb
• 分子名称: Tumor necrosis factor ligand superfamily member 14, membrane form, CD160 antigen, soluble form,Tumor necrosis factor receptor superfamily member 14, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: immunity, n-glycosylation, membrane, secreted protein, cytokine, jelly-roll fold, cysteine rich domain, signaling, cell membrane, secreted, immune system, immunoglobulin superfamily, tnf
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 136542.53

構造登録者

Liu, W.,Ramagopal, U.,Garrett-Thompson, S.C.,Fedorov, E.,Bonanno, J.B.,Almo, S.C. (登録日: 2021-05-11, 公開日: 2021-10-27, 最終更新日: 2023-10-18)

• 主引用文献: Liu, W.,Chou, T.F.,Garrett-Thomson, S.C.,Seo, G.Y.,Fedorov, E.,Ramagopal, U.A.,Bonanno, J.B.,Wang, Q.,Kim, K.,Garforth, S.J.,Kakugawa, K.,Cheroutre, H.,Kronenberg, M.,Almo, S.C.; HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.; J.Exp.Med., 218:-, 2021; PubMed: 34709351; DOI: 10.1084/jem.20211112

実験手法

X-RAY DIFFRACTION (3.5 Å)