7MNM

Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) T585M mutant in complex with Fab fragment

Summary for 7MNM

• Entry DOI: 10.2210/pdb7mnm/pdb
• Descriptor: E3 SUMO-protein ligase RanBP2, Antibody Fab14 Heavy Chain, Antibody Fab14 Light Chain (3 entities in total)
• Functional Keywords: nuclear pore complex component, nucleocytoplasmic transport, transport protein, transport protein-immune system complex, transport protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 270175.85

Authors

Bley, C.J.,Nie, S.,Mobbs, G.W.,Petrovic, S.,Gres, A.T.,Liu, X.,Mukherjee, S.,Harvey, S.,Huber, F.M.,Lin, D.H.,Brown, B.,Tang, A.W.,Rundlet, E.J.,Correia, A.R.,Chen, S.,Regmi, S.G.,Stevens, T.A.,Jette, C.A.,Dasso, M.,Patke, A.,Palazzo, A.F.,Kossiakoff, A.A.,Hoelz, A. (deposition date: 2021-05-01, release date: 2022-06-15, Last modification date: 2023-10-18)

• Primary citation: Bley, C.J.,Nie, S.,Mobbs, G.W.,Petrovic, S.,Gres, A.T.,Liu, X.,Mukherjee, S.,Harvey, S.,Huber, F.M.,Lin, D.H.,Brown, B.,Tang, A.W.,Rundlet, E.J.,Correia, A.R.,Chen, S.,Regmi, S.G.,Stevens, T.A.,Jette, C.A.,Dasso, M.,Patke, A.,Palazzo, A.F.,Kossiakoff, A.A.,Hoelz, A.; Architecture of the cytoplasmic face of the nuclear pore.; Science, 376:eabm9129-eabm9129, 2022; PubMed: 35679405; DOI: 10.1126/science.abm9129

Experimental method

X-RAY DIFFRACTION (4.7 Å)