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7MNM

Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) T585M mutant in complex with Fab fragment

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
E3 SUMO-protein ligase RanBP2polymer75386352.82UniProt (P49792)Homo sapiens (Human)358 kDa nucleoporin,Nuclear pore complex protein Nup358,Nucleoporin Nup358,Ran-binding protein 2,RanBP2,p270
2C, E
(H, K)
Antibody Fab14 Heavy Chainpolymer24025476.32Homo sapiens
3D, F
(L, M)
Antibody Fab14 Light Chainpolymer21523258.82Homo sapiens
Sequence modifications
A, B: 1 - 752 (UniProt: P49792)
PDBExternal DatabaseDetails
Ser 0-expression tag
Met 585Thr 585engineered mutation
Met 599Ile 599engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight270175.8
All*Total formula weight270175.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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