7MNM

Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) T585M mutant in complex with Fab fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	E3 SUMO-protein ligase RanBP2	polymer	753	86352.8	2	UniProt (P49792) In PDB	Homo sapiens (Human)	358 kDa nucleoporin,Nuclear pore complex protein Nup358,Nucleoporin Nup358,Ran-binding protein 2,RanBP2,p270
2	H, K	Antibody Fab14 Heavy Chain	polymer	240	25476.3	2		Homo sapiens
3	L, M	Antibody Fab14 Light Chain	polymer	215	23258.8	2		Homo sapiens

Sequence modifications

A, B: 1 - 752 (UniProt: P49792)

PDB	External Database	Details
Ser 0	-	expression tag
Met 585	Thr 585	engineered mutation
Met 599	Ile 599	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	270175.8
All*	Total formula weight	270175.8

*Water molecules are not included.