7MKK

Crystal structure of Drosophila Panoramix in complex with Sov NTD

Summary for 7MKK

Entry DOI	10.2210/pdb7mkk/pdb
Descriptor	Small ovary, isoform A, Protein panoramix (3 entities in total)
Functional Keywords	piwi, transposon silencing, heterochromatin formation, pirna pathway, transcriptional silencing, rna binding-metal binding protein complex, rna binding/metal binding protein
Biological source	Drosophila melanogaster (Fruit fly) More
Total number of polymer chains	8
Total formula weight	49413.24
Authors	Wang, J.,Patel, D.J. (deposition date: 2021-04-24, release date: 2022-02-02, Last modification date: 2024-05-22)
Primary citation	Andreev, V.I.,Yu, C.,Wang, J.,Schnabl, J.,Tirian, L.,Gehre, M.,Handler, D.,Duchek, P.,Novatchkova, M.,Baumgartner, L.,Meixner, K.,Sienski, G.,Patel, D.J.,Brennecke, J. Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery. Nat.Struct.Mol.Biol., 29:130-142, 2022 Cited by PubMed: 35173350 DOI: 10.1038/s41594-022-00721-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation