7MHZ

Human Hedgehog acyltransferase (HHAT) in complex with a palmitoylated Hedgehog peptide product and a Fab antibody fragment

7MHZ の概要

• エントリーDOI: 10.2210/pdb7mhz/pdb
• EMDBエントリー: 23837
• 分子名称: Sonic hedgehog protein N-product peptide, Protein-cysteine N-palmitoyltransferase HHAT, 3H02 Fab heavy chain, ... (8 entities in total)
• 機能のキーワード: mboat, goat, porcupine, acyl transferase, membrane protein, membrane enzyme, er, palmitoyl-coa, transferase-immune system complex, transferase/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 148470.20

構造登録者

Long, S.B.,Jiang, Y. (登録日: 2021-04-16, 公開日: 2021-06-16, 最終更新日: 2024-10-09)

• 主引用文献: Jiang, Y.,Benz, T.L.,Long, S.B.; Substrate and product complexes reveal mechanisms of Hedgehog acylation by HHAT.; Science, 372:1215-1219, 2021; PubMed: 34112694; DOI: 10.1126/science.abg4998

実験手法

ELECTRON MICROSCOPY (3.2 Å)