7MHE

Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7957

This is a non-PDB format compatible entry.

Summary for 7MHE

• Entry DOI: 10.2210/pdb7mhe/pdb
• Related: 7MHD
• Descriptor: Fatty acid synthase, 4-{4-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]benzene-1-sulfonyl}morpholine, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: thioesterase domain, fatty acid synthase, fasn-te, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 32991.22

Authors

Aleshin, A.E.,Lambert, L.,Liddington, R.C.,Cosford, N. (deposition date: 2021-04-15, release date: 2022-04-20, Last modification date: 2023-10-18)

• Primary citation: Aleshin, A.E.,Lambert, L.,Liddington, R.C.,Cosford, N.; Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)