7MHE
Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7957
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Fatty acid synthase | polymer | 298 | 32524.7 | 1 | UniProt (P49327) Pfam (PF00975) | Homo sapiens (Human) | Type I fatty acid synthase |
| 2 | B (AAA) | 4-{4-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]benzene-1-sulfonyl}morpholine | non-polymer | 404.5 | 1 | Chemie (ZEG) | |||
| 3 | C (AAA) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (AAA) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
AAA: 215 - 503 (UniProt: P49327)
| PDB | External Database | Details |
|---|---|---|
| Gly 207 | - | expression tag |
| Ser 208 | - | expression tag |
| Gly 209 | - | expression tag |
| Gly 210 | - | expression tag |
| Gly 211 | - | expression tag |
| Gly 212 | - | expression tag |
| Gly 213 | - | expression tag |
| Ser 214 | - | expression tag |
| His 504 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32524.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 466.5 | |
| All* | Total formula weight | 32991.2 |
