7MHD

Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635

7MHD の概要

• エントリーDOI: 10.2210/pdb7mhd/pdb
• 分子名称: Fatty acid synthase, N,N-diethyl-4-{2-[(2-fluorophenyl)methyl]-1,3-thiazol-4-yl}benzene-1-sulfonamide (3 entities in total)
• 機能のキーワード: thioesterase domain, fatty acid synthase, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32929.19

構造登録者

Aleshin, A.E.,Lambert, L.,Liddington, R.C.,Cosford, N. (登録日: 2021-04-15, 公開日: 2022-04-20, 最終更新日: 2023-10-18)

• 主引用文献: Aleshin, A.E.,Lambert, L.,Liddington, R.C.,Cosford, N.; Thioesterase Domain of Human Fatty Acid Synthase (FASN-TE) binding a competitive inhibitor SBP-7635; To Be Published,

実験手法

X-RAY DIFFRACTION (2.03 Å)