7ME8

The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-Q114 rotamer conformation at 1.60 Angstrom resolution

7ME8 の概要

• エントリーDOI: 10.2210/pdb7me8/pdb
• 関連するPDBエントリー: 4KKX 4WX2 4Y6G 4ZQC 5BW6 7KU9 7LY8 7M2L 7M3S
• 分子名称: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (8 entities in total)
• 機能のキーワード: inhibitor, internal aldimine, lyase
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72385.16

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2021-04-06, 公開日: 2021-10-13, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-Q114 rotamer conformation at 1.60 Angstrom resolution.; To be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)