7ME8

The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-Q114 rotamer conformation at 1.60 Angstrom resolution

Summary for 7ME8

Entry DOI	10.2210/pdb7me8/pdb
Related	4KKX 4WX2 4Y6G 4ZQC 5BW6 7KU9 7LY8 7M2L 7M3S
Descriptor	Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (8 entities in total)
Functional Keywords	inhibitor, internal aldimine, lyase
Biological source	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More
Total number of polymer chains	2
Total formula weight	72385.16
Authors	Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-04-06, release date: 2021-10-13, Last modification date: 2023-10-18)
Primary citation	Hilario, E.,Dunn, M.F.,Mueller, L.J. The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2-amino-1-ethylphosphate (F6F) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-Q114 rotamer conformation at 1.60 Angstrom resolution. To be Published,
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation