7MCJ

Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with compound 8918

Summary for 7MCJ

• Entry DOI: 10.2210/pdb7mcj/pdb
• Related: 7L9U 7LXI
• Descriptor: S-adenosylmethionine-dependent methyltransferase UmaA, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, NITRATE ION, ... (7 entities in total)
• Functional Keywords: ssgcid, short-chain fatty acid modification, compound 8918, structural genomics, seattle structural genomics center for infectious disease, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 2
• Total formula weight: 69279.92

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2021-04-02, release date: 2022-04-13, Last modification date: 2023-10-18)

• Primary citation: Abendroth, J.,Dranow, D.M.,Kahlert, G.,Scarry, S.M.,Grzegorzewicz, A.,Jackson, M.,Aube, J.,Sherman, D.R.,Gold, B.S.,Nathan, C.F.,Moritz, R.L.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal Structure of S-adenosylmethionine-dependent methyltransferase UmaA from Mycobacterium tuberculosis in complex with compound 8918; to be published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)