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7MA1

HIV-1 Protease (I84V) in Complex with GRL-98065

Summary for 7MA1
Entry DOI10.2210/pdb7ma1/pdb
DescriptorProtease, SULFATE ION, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE, ... (4 entities in total)
Functional Keywordshiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
Total number of polymer chains2
Total formula weight23172.90
Authors
Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-27, Last modification date: 2023-10-18)
Primary citationLockbaum, G.J.,Schiffer, C.A.
HIV-1 Protease (I84V) in Complex with GRL-98065
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.848 Å)
Structure validation

221716

PDB entries from 2024-06-26

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