7MA1
HIV-1 Protease (I84V) in Complex with GRL-98065
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Protease | polymer | 99 | 10817.8 | 2 | UniProt (P03367) Pfam (PF00077) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 (HIV-1) | PR,Retropepsin |
| 2 | B, A | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 3 | A | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(2S,3R)-3-HYDROXY-4-(N-ISOBUTYLBENZO[D][1,3]DIOXOLE-5-SULFONAMIDO)-1-PHENYLBUTAN-2-YLCARBAMATE | non-polymer | 576.7 | 1 | Chemie (065) | |||
| 4 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 507 | conflict |
| Asn 37 | Ser 537 | conflict |
| Val 84 | Ile 584 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21635.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1537.3 | |
| All* | Total formula weight | 23172.9 |
