7M5X

Human ATP13A2 in the outward-facing E2 state bound to spermine and beryllium fluoride

Summary for 7M5X

Entry DOI	10.2210/pdb7m5x/pdb
EMDB information	23684
Descriptor	Polyamine-transporting ATPase 13A2, 2-acetamido-2-deoxy-beta-D-glucopyranose, SPERMINE (FULLY PROTONATED FORM), ... (13 entities in total)
Functional Keywords	ion transport inhibited state, membrane protein, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	136506.51
Authors	Lee, K.P.K. (deposition date: 2021-03-25, release date: 2022-03-30, Last modification date: 2022-04-27)
Primary citation	Tillinghast, J.,Drury, S.,Bowser, D.,Benn, A.,Lee, K.P.K. Structural mechanisms for gating and ion selectivity of the human polyamine transporter ATP13A2. Mol.Cell, 81:4650-4662.e4, 2021 Cited by PubMed: 34715014 DOI: 10.1016/j.molcel.2021.10.002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation