7M5X
Human ATP13A2 in the outward-facing E2 state bound to spermine and beryllium fluoride
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polyamine-transporting ATPase 13A2 | polymer | 1189 | 129933.1 | 1 | UniProt (Q9NQ11) Pfam (PF12409) Pfam (PF00122) | Homo sapiens (human) | |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 1 | Chemie (BEF) | |||
| 4 | D, F, I (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 3 | Chemie (Y01) | |||
| 5 | E (A) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
| 6 | G, H, V, W (A) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
| 7 | J, K, L, M, N... (A) | DECANE | non-polymer | 142.3 | 10 | Chemie (D10) | |||
| 8 | P (A) | TETRADECANE | non-polymer | 198.4 | 1 | Chemie (C14) | |||
| 9 | Q (A) | DODECANE | non-polymer | 170.3 | 1 | Chemie (D12) | |||
| 10 | X (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 11 | Y (A) | SPERMINE (FULLY PROTONATED FORM) | non-polymer | 206.4 | 1 | Chemie (SPK) | |||
| 12 | Z (A) | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate | non-polymer | 746.6 | 1 | Chemie (EUJ) | |||
| 13 | AA (A) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 1 - 1180 (UniProt: Q9NQ11)
| PDB | External Database | Details |
|---|---|---|
| Ser 1181 | - | expression tag |
| Asn 1182 | - | expression tag |
| Ser 1183 | - | expression tag |
| Leu 1184 | - | expression tag |
| Glu 1185 | - | expression tag |
| Val 1186 | - | expression tag |
| Leu 1187 | - | expression tag |
| Phe 1188 | - | expression tag |
| Gln 1189 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 129933.1 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 6573.4 | |
| All* | Total formula weight | 136506.5 |
