7M56
Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine
Summary for 7M56
Entry DOI | 10.2210/pdb7m56/pdb |
Descriptor | Nitric oxide synthase, endothelial, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (10 entities in total) |
Functional Keywords | nitric oxide synthase inhibitor heme enzymes, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 102520.81 |
Authors | Li, H.,Poulos, T.L. (deposition date: 2021-03-22, release date: 2022-03-30, Last modification date: 2023-10-18) |
Primary citation | Lewis, M.C.,Weerawarnab, P.M.,Li, H.,Silverman, R.B.,Poulos, T.L. Inhibition of bacterial nitric oxide synthase as an antimicrobial tool in fighting some antibiotic-resistant pathogens To be published, |
Experimental method | X-RAY DIFFRACTION (1.957 Å) |
Structure validation
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