7M56

Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine

Summary for 7M56

• Entry DOI: 10.2210/pdb7m56/pdb
• Descriptor: Nitric oxide synthase, endothelial, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (10 entities in total)
• Functional Keywords: nitric oxide synthase inhibitor heme enzymes, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 102520.81

Authors

Li, H.,Poulos, T.L. (deposition date: 2021-03-22, release date: 2022-03-30, Last modification date: 2023-10-18)

• Primary citation: Lewis, M.C.,Weerawarnab, P.M.,Li, H.,Silverman, R.B.,Poulos, T.L.; Inhibition of bacterial nitric oxide synthase as an antimicrobial tool in fighting some antibiotic-resistant pathogens; To be published,

Experimental method

X-RAY DIFFRACTION (1.957 Å)