7M3H

Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor

Summary for 7M3H

• Entry DOI: 10.2210/pdb7m3h/pdb
• Related: 7M1Z
• Descriptor: Hydroxymethylglutaryl-CoA reductase, degradative, 5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic acid, SULFATE ION, ... (5 entities in total)
• Functional Keywords: ligands, metabolism, drug target, hmg-coa, mevalonate, prokaryote., antibiotic
• Biological source: Enterococcus faecalis (Streptococcus faecalis)
• Total number of polymer chains: 2
• Total formula weight: 93238.19

Authors

Bose, S.,Steussy, C.N.,Stauffacher, C.V. (deposition date: 2021-03-18, release date: 2022-09-21, Last modification date: 2023-10-18)

• Primary citation: Bose, S.,Steussy, C.N.,Stauffacher, C.V.; Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.27 Å)