7M31

Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Thymine and NADPH Anaerobically

Summary for 7M31

Entry DOI	10.2210/pdb7m31/pdb
Descriptor	Dihydropyrimidine dehydrogenase [NADP(+)], IRON/SULFUR CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... (8 entities in total)
Functional Keywords	dihydropyrimidine dehydrogenase, dpd, mutant, uracil, flavin, soaking, ligand, fmn, fad, flavoprotein
Biological source	Sus scrofa (Pig)
Total number of polymer chains	4
Total formula weight	460536.14
Authors	Butrin, A.,Beaupre, B.,Forouzesh, D.,Liu, D.,Moran, G. (deposition date: 2021-03-18, release date: 2021-06-09, Last modification date: 2023-10-18)
Primary citation	Beaupre, B.A.,Forouzesh, D.C.,Butrin, A.,Liu, D.,Moran, G.R. Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase. Biochemistry, 60:1764-1775, 2021 Cited by PubMed: 34032117 DOI: 10.1021/acs.biochem.1c00243 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation