7M31
Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Thymine and NADPH Anaerobically
Summary for 7M31
Entry DOI | 10.2210/pdb7m31/pdb |
Descriptor | Dihydropyrimidine dehydrogenase [NADP(+)], IRON/SULFUR CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... (8 entities in total) |
Functional Keywords | dihydropyrimidine dehydrogenase, dpd, mutant, uracil, flavin, soaking, ligand, fmn, fad, flavoprotein |
Biological source | Sus scrofa (Pig) |
Total number of polymer chains | 4 |
Total formula weight | 460536.14 |
Authors | Butrin, A.,Beaupre, B.,Forouzesh, D.,Liu, D.,Moran, G. (deposition date: 2021-03-18, release date: 2021-06-09, Last modification date: 2023-10-18) |
Primary citation | Beaupre, B.A.,Forouzesh, D.C.,Butrin, A.,Liu, D.,Moran, G.R. Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase. Biochemistry, 60:1764-1775, 2021 Cited by PubMed: 34032117DOI: 10.1021/acs.biochem.1c00243 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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