7LYX

Crystal structure of human CYP8B1 in complex with (S)-tioconazole

Summary for 7LYX

• Entry DOI: 10.2210/pdb7lyx/pdb
• Descriptor: 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, (S)-Tioconazole, ... (6 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 58265.13

Authors

Liu, J.,Scott, E.E. (deposition date: 2021-03-08, release date: 2022-08-17, Last modification date: 2023-10-25)

• Primary citation: Liu, J.,Carlson, H.A.,Scott, E.E.; The structure and characterization of human cytochrome P450 8B1 supports future drug design for nonalcoholic fatty liver disease and diabetes.; J.Biol.Chem., 298:102344-102344, 2022; PubMed: 35944583; DOI: 10.1016/j.jbc.2022.102344

Experimental method

X-RAY DIFFRACTION (2.6 Å)