7LYX

Crystal structure of human CYP8B1 in complex with (S)-tioconazole

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005506	molecular_function	iron ion binding
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0006629	biological_process	lipid metabolic process
A	0006694	biological_process	steroid biosynthetic process
A	0006699	biological_process	bile acid biosynthetic process
A	0008397	molecular_function	sterol 12-alpha-hydroxylase activity
A	0016125	biological_process	sterol metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0031667	biological_process	response to nutrient levels
A	0045797	biological_process	positive regulation of intestinal cholesterol absorption
A	0046872	molecular_function	metal ion binding
A	0070723	biological_process	response to cholesterol

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"description":"axial binding residue","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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