7LW7

Human Exonuclease 5 crystal structure

Summary for 7LW7

• Entry DOI: 10.2210/pdb7lw7/pdb
• Descriptor: Exonuclease V, GLYCEROL, IRON/SULFUR CLUSTER, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 39673.09

Authors

Tsai, C.L.,Tainer, J.A. (deposition date: 2021-02-27, release date: 2021-07-14, Last modification date: 2024-03-06)

• Primary citation: Hambarde, S.,Tsai, C.L.,Pandita, R.K.,Bacolla, A.,Maitra, A.,Charaka, V.,Hunt, C.R.,Kumar, R.,Limbo, O.,Le Meur, R.,Chazin, W.J.,Tsutakawa, S.E.,Russell, P.,Schlacher, K.,Pandita, T.K.,Tainer, J.A.; EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.; Mol.Cell, 81:2989-, 2021; PubMed: 34197737; DOI: 10.1016/j.molcel.2021.05.027

Experimental method

X-RAY DIFFRACTION (2.5 Å)