7LW3

Structure of SARS-CoV-2 nsp16/nsp10 complex in presence of Cap-1 analog (m7GpppAmU) and SAH

Summary for 7LW3

• Entry DOI: 10.2210/pdb7lw3/pdb
• Descriptor: 2'-O-methyltransferase, Non-structural protein 10, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (9 entities in total)
• Functional Keywords: product complex, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 2
• Total formula weight: 50093.68

Authors

Gupta, Y.K.,Viswanathan, T.,Misra, A.,Qi, S. (deposition date: 2021-02-27, release date: 2021-05-05, Last modification date: 2023-10-18)

• Primary citation: Viswanathan, T.,Misra, A.,Chan, S.H.,Qi, S.,Dai, N.,Arya, S.,Martinez-Sobrido, L.,Gupta, Y.K.; A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2'-O methylation of its first nucleotide.; Nat Commun, 12:3287-3287, 2021; PubMed: 34078893; DOI: 10.1038/s41467-021-23594-y

Experimental method

X-RAY DIFFRACTION (2.3 Å)