7LUS
IgG2 Fc Charge Pair Mutation version 1 (CPMv1)
Summary for 7LUS
Entry DOI | 10.2210/pdb7lus/pdb |
Descriptor | Immunoglobulin heavy constant gamma 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | fragment crystallizable, fc, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 50161.05 |
Authors | Sudom, A.,Whittington, D.,Garces, F.,Wang, Z. (deposition date: 2021-02-23, release date: 2021-09-15, Last modification date: 2023-10-18) |
Primary citation | Estes, B.,Sudom, A.,Gong, D.,Whittington, D.A.,Li, V.,Mohr, C.,Li, D.,Riley, T.P.,Shi, S.D.,Zhang, J.,Garces, F.,Wang, Z. Next generation Fc scaffold for multispecific antibodies. Iscience, 24:103447-103447, 2021 Cited by PubMed: 34877503DOI: 10.1016/j.isci.2021.103447 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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