7LTP

The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and the product L-tryptophan at the enzyme beta-site at 1.47 Angstrom resolution

Summary for 7LTP

• Entry DOI: 10.2210/pdb7ltp/pdb
• Related: 5CGQ 7JLL 7LKL
• Descriptor: Tryptophan synthase alpha chain, DIMETHYL SULFOXIDE, CHLORIDE ION, ... (12 entities in total)
• Functional Keywords: inhibitor, internal aldimine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 73570.42

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-02-19, release date: 2022-02-23, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and the product L-tryptophan at the enzyme beta-site at 1.47 Angstrom resolution.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.47 Å)