7LTP

The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and the product L-tryptophan at the enzyme beta-site at 1.47 Angstrom resolution

7LTP の概要

• エントリーDOI: 10.2210/pdb7ltp/pdb
• 関連するPDBエントリー: 5CGQ 7JLL 7LKL
• 分子名称: Tryptophan synthase alpha chain, DIMETHYL SULFOXIDE, CHLORIDE ION, ... (12 entities in total)
• 機能のキーワード: inhibitor, internal aldimine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 73570.42

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2021-02-19, 公開日: 2022-02-23, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The internal aldimine form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site and the product L-tryptophan at the enzyme beta-site at 1.47 Angstrom resolution.; To be Published,

実験手法

X-RAY DIFFRACTION (1.47 Å)