7LSF
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Western Subtype)
Summary for 7LSF
Entry DOI | 10.2210/pdb7lsf/pdb |
Descriptor | T025 Fab Heavy Chain, T025 Fab Light Chain, Envelope protein E, ... (6 entities in total) |
Functional Keywords | tick-borne encephalitis virus, antibody, ediii, tbev, immune system, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 61918.08 |
Authors | Keeffe, J.R.,Bjorkman, P.J. (deposition date: 2021-02-18, release date: 2021-04-07, Last modification date: 2023-10-18) |
Primary citation | Agudelo, M.,Palus, M.,Keeffe, J.R.,Bianchini, F.,Svoboda, P.,Salat, J.,Peace, A.,Gazumyan, A.,Cipolla, M.,Kapoor, T.,Guidetti, F.,Yao, K.H.,Elsterova, J.,Teislerova, D.,Chrdle, A.,Honig, V.,Oliveira, T.,West, A.P.,Lee, Y.E.,Rice, C.M.,MacDonald, M.R.,Bjorkman, P.J.,Ruzek, D.,Robbiani, D.F.,Nussenzweig, M.C. Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease. J.Exp.Med., 218:-, 2021 Cited by PubMed: 33831141DOI: 10.1084/jem.20210236 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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