7LSF
Crystal structure of the human neutralizing antibody Fab fragment T025 bound to TBEV EDIII (Western Subtype)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | T025 Fab Heavy Chain | polymer | 232 | 24834.7 | 1 | Homo sapiens | ||
| 2 | B (L) | T025 Fab Light Chain | polymer | 214 | 23425.0 | 1 | Homo sapiens | ||
| 3 | C (E) | Envelope protein E | polymer | 120 | 13520.3 | 1 | UniProt (E3UMN9) Pfam (PF02832) UniProt (by SIFTS) (P14336) | Tick-borne encephalitis virus (WESTERN SUBTYPE) | |
| 4 | D, F (H, E) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | E (L) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | G, H, I (H, L, E) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
E: 299 - 397 (UniProt: E3UMN9)
| PDB | External Database | Details |
|---|---|---|
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| Gly 404 | - | expression tag |
| Leu 405 | - | expression tag |
| Asn 406 | - | expression tag |
| Asp 407 | - | expression tag |
| Ile 408 | - | expression tag |
| Phe 409 | - | expression tag |
| Glu 410 | - | expression tag |
| Ala 411 | - | expression tag |
| Gln 412 | - | expression tag |
| Lys 413 | - | expression tag |
| Ile 414 | - | expression tag |
| Glu 415 | - | expression tag |
| Trp 416 | - | expression tag |
| His 417 | - | expression tag |
| Glu 418 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61780.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 138.1 | |
| All* | Total formula weight | 61918.1 |
