7LR0

Structure of squirrel TRPV1 in complex with capsaicin

7LR0 の概要

• エントリーDOI: 10.2210/pdb7lr0/pdb
• 関連するPDBエントリー: 7LQY 7LQZ
• EMDBエントリー: 23491 23492 23493
• 分子名称: Osm-9-like TRP channel 1, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (6E)-N-(4-hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide, ... (4 entities in total)
• 機能のキーワード: transient receptor potential v family member 1, trp channel, trpv1 full length, trpv1 wild type, capsaicin, membrane protein
• 由来する生物種: Ictidomys tridecemlineatus (Thirteen-lined ground squirrel, Spermophilus tridecemlineatus)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 406137.89

構造登録者

Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. (登録日: 2021-02-15, 公開日: 2021-04-21, 最終更新日: 2024-03-06)

• 主引用文献: Nadezhdin, K.D.,Neuberger, A.,Nikolaev, Y.A.,Murphy, L.A.,Gracheva, E.O.,Bagriantsev, S.N.,Sobolevsky, A.I.; Extracellular cap domain is an essential component of the TRPV1 gating mechanism.; Nat Commun, 12:2154-2154, 2021; PubMed: 33846324; DOI: 10.1038/s41467-021-22507-3

実験手法

ELECTRON MICROSCOPY (3.81 Å)