7LOT

Human PPAR Gamma LBD in Complex with Tetrazole Compound N-{3-[(4-methylbenzyl)oxy]benzyl}-2H-tetrazol-5-amine.

Summary for 7LOT

Entry DOI	10.2210/pdb7lot/pdb
Descriptor	Peroxisome proliferator-activated receptor gamma, ~{N}-[[3-[(4-methylphenyl)methoxy]phenyl]methyl]-1~{H}-1,2,3,4-tetrazol-5-amine (3 entities in total)
Functional Keywords	ppar gamma, complex, tetrazole, gene regulation
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	64060.40
Authors	de Paula, K.,Nascimento, A.S. (deposition date: 2021-02-10, release date: 2021-02-24, Last modification date: 2023-10-18)
Primary citation	de Paula, K.,Santos, J.C.,Mafud, A.C.,Nascimento, A.S. Tetrazoles as PPAR gamma ligands: A structural and computational investigation. J.Mol.Graph.Model., 106:107932-107932, 2021 Cited by PubMed: 33946041 DOI: 10.1016/j.jmgm.2021.107932 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation