7LEP
The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution
Summary for 7LEP
Entry DOI | 10.2210/pdb7lep/pdb |
EMDB information | 23292 |
Descriptor | Mix of AMPAR subunits (GluA1, GluA3, and GluA4), 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, N-OCTANE, ... (12 entities in total) |
Functional Keywords | native hippocampal ion channel, membrane protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 291860.09 |
Authors | Yu, J.,Rao, P.,Gouaux, E. (deposition date: 2021-01-14, release date: 2021-05-12, Last modification date: 2021-06-30) |
Primary citation | Yu, J.,Rao, P.,Clark, S.,Mitra, J.,Ha, T.,Gouaux, E. Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition. Nature, 594:448-453, 2021 Cited by PubMed: 33981040DOI: 10.1038/s41586-021-03540-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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