7LBC
Structure of human GGT1 in complex with Lnt2-65 compound
Summary for 7LBC
| Entry DOI | 10.2210/pdb7lbc/pdb |
| Descriptor | Glutathione hydrolase 1 heavy chain, Glutathione hydrolase 1 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | substrate-enzyme complex, ntn-hydrolase family, glycoprotein, n-glycosylation, cell surface, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 60011.12 |
| Authors | Terzyan, S.S.,Hanigan, M. (deposition date: 2021-01-07, release date: 2022-02-09, Last modification date: 2023-10-18) |
| Primary citation | Nguyen, L.,Schultz, D.C.,Terzyan, S.S.,Rezaei, M.,Songb, J.,Li, C.,You, Y.,Hanigan, M.H. Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase. Bioorg.Med.Chem., 73:116986-116986, 2022 Cited by PubMed: 36208545DOI: 10.1016/j.bmc.2022.116986 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.28 Å) |
Structure validation
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