7LBC
Structure of human GGT1 in complex with Lnt2-65 compound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glutathione hydrolase 1 heavy chain | polymer | 353 | 38533.7 | 1 | UniProt (P19440) Pfam (PF01019) In PDB | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 2 | B | Glutathione hydrolase 1 light chain | polymer | 189 | 20014.4 | 1 | UniProt (P19440) Pfam (PF01019) In PDB | Homo sapiens (Human) | GGT 1,Gamma-glutamyltransferase 1,Glutathione hydrolase 1,Leukotriene-C4 hydrolase |
| 3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | B | (2R)-2-[(2-aminoethyl)amino]-4-boronobutanoic acid | non-polymer | 190.0 | 1 | Chemie (XSA) | |||
| 6 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 28 - 380 (UniProt: P19440)
| PDB | External Database | Details |
|---|---|---|
| Ala 272 | Val 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58548.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1463.0 | |
| All* | Total formula weight | 60011.1 |
