7LB3

Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580

7LB3 の概要

• エントリーDOI: 10.2210/pdb7lb3/pdb
• 分子名称: Transcription initiation factor TFIID subunit 1, 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-indazole, 1,2-ETHANEDIOL, ... (4 entities in total)
• 機能のキーワード: bromodomain, taf1, non-bet, bet, kinase inhibitor, atr, dual brd-kinase, transferase, gene regulation
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16357.39

構造登録者

Karim, M.R.,Schonbrunn, E. (登録日: 2021-01-07, 公開日: 2022-01-12, 最終更新日: 2023-10-18)

• 主引用文献: Karim, M.R.,Schonbrunn, E.; Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ZS1-580; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)