7L9T

Crystal Structure of Dihydrofolate reductase from Mycolicibacterium smegmatis in complex with SDDC-0001565 inhibitor

Summary for 7L9T

• Entry DOI: 10.2210/pdb7l9t/pdb
• Descriptor: Dihydrofolate reductase, 3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, SULFATE ION, ... (5 entities in total)
• Functional Keywords: ssgcid, dihydrofolate reductase, sddc-0001565, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase
• Biological source: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
• Total number of polymer chains: 1
• Total formula weight: 19103.59

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2021-01-05, release date: 2021-01-20, Last modification date: 2023-10-18)

• Primary citation: DeBouver, N.D.,Bolejack, M.J.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal Structure of Acetyl-coenzyme A synthetase synthetase from Coccidioides immitis in complex with PRX; to be published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)