7L5B

Crystallographic structure of neutralizing antibody 2-15 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD).

7L5B の概要

• エントリーDOI: 10.2210/pdb7l5b/pdb
• 分子名称: Spike protein S1, 2-15 Heavy chain, 2-15 Light Chain (3 entities in total)
• 機能のキーワード: spike protein s1, receptor binding protein sars cov-2, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 73986.70

構造登録者

Reddem, E.R.,Shapiro, L. (登録日: 2020-12-21, 公開日: 2021-02-10, 最終更新日: 2023-10-18)

• 主引用文献: Rapp, M.,Guo, Y.,Reddem, E.R.,Yu, J.,Liu, L.,Wang, P.,Cerutti, G.,Katsamba, P.,Bimela, J.S.,Bahna, F.A.,Mannepalli, S.M.,Zhang, B.,Kwong, P.D.,Huang, Y.,Ho, D.D.,Shapiro, L.,Sheng, Z.; Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class.; Cell Rep, 35:108950-108950, 2021; PubMed: 33794145; DOI: 10.1016/j.celrep.2021.108950

実験手法

X-RAY DIFFRACTION (3.18 Å)