7L2C
Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD)
Summary for 7L2C
Entry DOI | 10.2210/pdb7l2c/pdb |
Descriptor | Spike glycoprotein, 2-51 heavy chain, 2-51 light chain, ... (10 entities in total) |
Functional Keywords | covid-19, sars-cov-2, viral protein, spike glycoprotein, n-terminal domain, ntd, neutralizing antibody, 2-51, fab, immune system, immune system-viral protein complex, immune system/viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 6 |
Total formula weight | 177328.13 |
Authors | Cerutti, G.,Reddem, E.R.,Shapiro, L. (deposition date: 2020-12-16, release date: 2021-02-10, Last modification date: 2023-10-18) |
Primary citation | Cerutti, G.,Guo, Y.,Zhou, T.,Gorman, J.,Lee, M.,Rapp, M.,Reddem, E.R.,Yu, J.,Bahna, F.,Bimela, J.,Huang, Y.,Katsamba, P.S.,Liu, L.,Nair, M.S.,Rawi, R.,Olia, A.S.,Wang, P.,Zhang, B.,Chuang, G.Y.,Ho, D.D.,Sheng, Z.,Kwong, P.D.,Shapiro, L. Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29:819-, 2021 Cited by PubMed: 33789084DOI: 10.1016/j.chom.2021.03.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.65 Å) |
Structure validation
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