7L1P

HIV Integrase Core domain (IN) in complex with dimer-spanning ligand

Summary for 7L1P

• Entry DOI: 10.2210/pdb7l1p/pdb
• Related: 6KVA
• Descriptor: Integrase, (2-{[3-(4-{2-[(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzene-1-carbonyl)amino]ethyl}piperazine-1-carbonyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid, IODIDE ION, ... (5 entities in total)
• Functional Keywords: inhibitor, hiv integrase, transferase-transferase inhibitor complex, transferase-transferase inhibitor
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 37974.26

Authors

Gorman, M.A.,Parker, M.W. (deposition date: 2020-12-15, release date: 2021-12-22)

• Primary citation: Gorman, M.A.,Parker, M.W.; HIV Integrase core domain in complex with inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)