7L1P
HIV Integrase Core domain (IN) in complex with dimer-spanning ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Integrase | polymer | 163 | 17889.3 | 2 | UniProt (Q76353) Pfam (PF00665) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | A | (2-{[3-(4-{2-[(3-{[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}benzene-1-carbonyl)amino]ethyl}piperazine-1-carbonyl)phenyl]ethynyl}-5-methyl-1-benzofuran-3-yl)acetic acid | non-polymer | 761.8 | 1 | Chemie (R2A) | |||
| 3 | A, B | IODIDE ION | non-polymer | 126.9 | 6 | Chemie (IOD) | |||
| 4 | A, B | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 60 | Chemie (HOH) |
Sequence modifications
A, B: 50 - 212 (UniProt: Q76353)
| PDB | External Database | Details |
|---|---|---|
| Glu 53 | Gln 53 | conflict |
| Ser 56 | Cys 56 | conflict |
| Glu 131 | Trp 131 | conflict |
| Lys 185 | Phe 185 | conflict |
| Glu 209 | Gln 209 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35778.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2195.7 | |
| All* | Total formula weight | 37974.3 |
