7L1H

The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.50 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site

7L1H の概要

• エントリーDOI: 10.2210/pdb7l1h/pdb
• 関連するPDBエントリー: 4HN4 6D0V 6VNT 6X0C 7KA1 7KQ9 7KWV 7L03
• 分子名称: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (10 entities in total)
• 機能のキーワード: inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74046.02

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2020-12-14, 公開日: 2021-12-29, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.50 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site; To be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)