7L03
The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and sodium ion at the metal coordination site at 1.60 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site
Summary for 7L03
Entry DOI | 10.2210/pdb7l03/pdb |
Related | 4HN4 6D0V 6VNT 6X0C 7KA1 7KQ9 7KWV |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (8 entities in total) |
Functional Keywords | inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella enterica subsp. enterica serovar Typhimurium More |
Total number of polymer chains | 2 |
Total formula weight | 72906.74 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-12-11, release date: 2021-12-22, Last modification date: 2023-10-18) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J. The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and sodium ion at the metal coordination site at 1.60 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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