7L1H

The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.50 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site

Summary for 7L1H

• Entry DOI: 10.2210/pdb7l1h/pdb
• Related: 4HN4 6D0V 6VNT 6X0C 7KA1 7KQ9 7KWV 7L03
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (10 entities in total)
• Functional Keywords: inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 74046.02

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-12-14, release date: 2021-12-29, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site at 1.50 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site; To be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)