7KZ0
Human MBD4 glycosylase domain bound to DNA containing substrate analog 2'-deoxy-pseudouridine
Summary for 7KZ0
Entry DOI | 10.2210/pdb7kz0/pdb |
Descriptor | Methyl-CpG-binding domain protein 4, DNA (5'-D(*CP*CP*AP*GP*CP*GP*(P2U)P*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*GP*CP*GP*CP*TP*GP*G)-3'), ... (6 entities in total) |
Functional Keywords | mbd4, protein-dna complex, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 28205.74 |
Authors | Pidugu, L.S.,Pozharski, E.,Drohat, A.C. (deposition date: 2020-12-09, release date: 2021-11-10, Last modification date: 2023-10-18) |
Primary citation | Pidugu, L.S.,Bright, H.,Lin, W.J.,Majumdar, C.,Van Ostrand, R.P.,David, S.S.,Pozharski, E.,Drohat, A.C. Structural Insights into the Mechanism of Base Excision by MBD4. J.Mol.Biol., 433:167097-167097, 2021 Cited by PubMed: 34107280DOI: 10.1016/j.jmb.2021.167097 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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