7KXW
Crystal structure of DCLK1-KD in complex with DCLK1-IN-1
Summary for 7KXW
Entry DOI | 10.2210/pdb7kxw/pdb |
Descriptor | Serine/threonine-protein kinase DCLK1, 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | kinase, doublecortin-like, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 64034.90 |
Authors | |
Primary citation | Patel, O.,Roy, M.J.,Kropp, A.,Hardy, J.M.,Dai, W.,Lucet, I.S. Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Commun Biol, 4:1105-1105, 2021 Cited by PubMed: 34545159DOI: 10.1038/s42003-021-02631-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.002 Å) |
Structure validation
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