7KW7

Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR

Summary for 7KW7

• Entry DOI: 10.2210/pdb7kw7/pdb
• EMDB information: 23050
• Descriptor: Heat shock protein HSP 90-alpha, Heat shock 70 kDa protein 1A, Stress-induced-phosphoprotein 1, ... (7 entities in total)
• Functional Keywords: client-loading, chaperone
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 459237.13

Authors

Wang, R.Y.,Noddings, C.M.,Kirschke, E.,Myasnikov, A.,Johnson, J.L.,Agard, D.A. (deposition date: 2020-11-30, release date: 2021-12-08, Last modification date: 2024-05-29)

• Primary citation: Wang, R.Y.,Noddings, C.M.,Kirschke, E.,Myasnikov, A.G.,Johnson, J.L.,Agard, D.A.; Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism.; Nature, 601:460-464, 2022; PubMed: 34937942; DOI: 10.1038/s41586-021-04252-1

Experimental method

ELECTRON MICROSCOPY (3.57 Å)