7KRZ
Human mitochondrial LONP1 in complex with Bortezomib
Summary for 7KRZ
Entry DOI | 10.2210/pdb7krz/pdb |
EMDB information | 23013 23019 23020 |
Descriptor | Lon protease homolog, mitochondrial, Endogenous co-purified substrate, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | aaa+, atpase, protease, mitochondrial, lonp1, lon, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 7 |
Total formula weight | 362209.14 |
Authors | Shin, M.,Watson, E.R.,Song, A.S.,Mindrebo, J.T.,Novick, S.R.,Griffin, P.,Wiseman, R.L.,Lander, G.C. (deposition date: 2020-11-20, release date: 2021-02-24, Last modification date: 2022-06-15) |
Primary citation | Shin, M.,Watson, E.R.,Song, A.S.,Mindrebo, J.T.,Novick, S.J.,Griffin, P.R.,Wiseman, R.L.,Lander, G.C. Structures of the human LONP1 protease reveal regulatory steps involved in protease activation. Nat Commun, 12:3239-3239, 2021 Cited by PubMed: 34050165DOI: 10.1038/s41467-021-23495-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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