7KRA

Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid nanodiscs

7KRA の概要

• エントリーDOI: 10.2210/pdb7kra/pdb
• EMDBエントリー: 11732 11733 23003 23033
• 分子名称: ER membrane protein complex subunit 1, Fab DH4 light chain, Unassigned helix, ... (13 entities in total)
• 機能のキーワード: er membrane protein complex, emc, membrane protein biogenesis, insertase, chaperone, endoplasmic, reticulum, membrane protein-immune system complex, membrane protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 311507.80

構造登録者

Miller-Vedam, L.E.,Schirle Oakdale, N.S.,Braeuning, B.,Boydston, E.A.,Sevillano, N.,Popova, K.D.,Bonnar, J.L.,Shurtleff, M.J.,Prabu, J.R.,Stroud, R.M.,Craik, C.S.,Schulman, B.A.,Weissman, J.S.,Frost, A. (登録日: 2020-11-19, 公開日: 2020-12-02, 最終更新日: 2020-12-09)

• 主引用文献: Miller-Vedam, L.E.,Brauning, B.,Popova, K.D.,Schirle Oakdale, N.T.,Bonnar, J.L.,Prabu, J.R.,Boydston, E.A.,Sevillano, N.,Shurtleff, M.J.,Stroud, R.M.,Craik, C.S.,Schulman, B.A.,Frost, A.,Weissman, J.S.; Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.; Elife, 9:-, 2020; PubMed: 33236988; DOI: 10.7554/eLife.62611

実験手法

ELECTRON MICROSCOPY (3.2 Å)