7KR5

Cryo-EM structure of the CRAC channel Orai in an open conformation; H206A gain-of-function mutation in complex with an antibody

7KR5 の概要

• エントリーDOI: 10.2210/pdb7kr5/pdb
• EMDBエントリー: 23002
• 分子名称: Calcium release-activated calcium channel protein 1, 19B5 Fab heavy chain, 19B5 Fab light chain, ... (4 entities in total)
• 機能のキーワード: ion channel, calcium, soce, crac, eukaryotic, open structure, membrane protein, amphiboles, cryo-em, transport protein-immune system complex, transport protein/immune system
• 由来する生物種: Drosophila melanogaster (Fruit fly); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 302422.40

構造登録者

Long, S.B.,Hou, X.,Outhwaite, I.R. (登録日: 2020-11-18, 公開日: 2020-12-09)

• 主引用文献: Hou, X.,Outhwaite, I.R.,Pedi, L.,Long, S.B.; Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation.; Elife, 9:-, 2020; PubMed: 33252040; DOI: 10.7554/eLife.62772

実験手法

ELECTRON MICROSCOPY (3.3 Å)